Capacity building and networking to make newborn screening for sickle cell disease a reality in Haiti
نویسندگان
چکیده
منابع مشابه
Neonatal Screening for Sickle Cell Disease in Southwest Iran
the risk of sickle cell complications that is a common hemoglobin disorder in Southwest Iran. This study aimed at determining the incidence of Sickle Cell Disease (SCD) and other Hemoglobinopathies in newborn being at risk based on ethnic origin. Materials and Methods: In this descriptive epidemiologic study, between September 2013 and September 2015, 8363 newborn blood samples were test...
متن کاملNeonatal Screening for Sickle Cell Disease in South West Iran: a Pilot Study
Background: Children affected with sickle cell disease (SCD) are at increased risk for severe morbidity and mortality, especially during the first 3-5 years of life. It is suggested that early treatment can improve the condition. The aim of this pilot study was to estimate the incidence of hemoglobin S (HbS) by umbilical cord blood screening in Khorramshahr and Abadan cities in southwest of Ira...
متن کاملNewborn screening for sickle cell disease using tandem mass spectrometry.
BACKGROUND Neonatal screening programs for sickle cell disease are now widespread in North American and European countries. Most programs apply isoelectric focusing or HPLC to detect hemoglobin variants. Because tandem mass spectrometry (MS/MS) is being used for screening of inherited metabolic disorders and allows protein identification, it was worth testing for hemoglobinopathy screening. M...
متن کاملNewborn Screening for Sickle Cell Disease: Socio-Ethical Implications
Newborn screening is now integrated into routine neonatal practice in many parts of the world, and the overall ethical acceptability of newborn screening programmes is well recognised.1 Although the procedure corresponds in essence to genetic screening, it is seldom referred to as such and is often categorised as a public health disease prevention programme aimed at early detection and treatmen...
متن کاملNewborn screening for sickle cell disease: necessary but not sufficient.
ickle cell disease is a global health problem that ffects > 300,000 newborns per year, predominantly in Subaharan Africa,1 where mortality is estimated to be > 50% y age 5 years for those with homozygous hemoglobin S HbSS).1 In Brazil, there are estimated to be > 30,000 indiiduals with sickle cell disease and 2,500 newborns per ear, making this the most common genetic disorder in the ountry.2 A...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Blood Advances
سال: 2018
ISSN: 2473-9529,2473-9537
DOI: 10.1182/bloodadvances.2018gs111997